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NCT06798857Completed

Exploration of the Relationship Between Mismatch Repair Status of Colorectal Cancer and Lymph Node Metastasis Patterns and Pathological High-risk Factors

Source: ClinicalTrials.gov · Last updated 2 Dec 2025

Brief summary (registry, in English)

This study analyzed the differences in clinical baseline features and survival outcomes between pMMR and dMMR patients. The aim is to evaluate the impact of MMR status on overall survival and disease-free survival of colorectal patients, and to explore the population exempt from extended resection, so as to provide evidence-based medical evidence for the relationship between MMR status, lymph node metastasis pattern and clinicopathological risk factors in colon cancer patients.

Status (registry)
Completed
Study type
Observational
Enrollment
1471 (actual)
First submitted
23 Jan 2025
Start date
14 Apr 2009
Primary completion date
7 Sept 2021
Lead sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
NCT number
NCT06798857

What you commit to

  • Study type: Observational
  • Participants enrolled: 1471
  • From 14 Apr 2009 to the primary completion date, 7 Sept 2021
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Concurrent distant metastasis
  • Receiving preoperative neoadjuvant therapy.

Other illness

  • Previous history of malignant tumors

Who the study is looking for

  • The preoperative diagnosis was primary colon adenocarcinoma;
  • Undergoing radical surgical treatment;
  • Postoperative immunohistochemistry to determine MMR status;
  • Having complete key clinical and follow-up data.

Age in the registry: 20 years to 90 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.