NCT06799182Completed
Periodontal Disease and Colorectal Cancer
The Influence of Periodontal Disease and Periodontal Treatment on Colorectal Cancer
Source: ClinicalTrials.gov · Last updated 29 Jan 2025
Brief summary (registry, in English)
The aim of this interventional study is to determine the impact of periodontal disease and periodontal treatment on patients with colorectal cancer. The main questions were: 1. Does periodontal treatment affect the levels of C-reactive protein in the blood of patients undergoing cancer treatment? 2. Can the investigators isolate periodontal pathogenic bacteria Fusobacterium nucleatum and Porphyromonas gingivalis from the mucosa of cancerous colon tissue using the method of quantitative culture? The investigators will compare the levels of C-reactive protein in the blood of patients undergoing treatment for colorectal cancer who have received periodontal treatment with patients who have not received periodontal treatment. CRP levels will be measured during the first examination with the oncological surgeon, on the first and second day after the surgical procedure, and during the first follow-up with the oncological surgeon. Additionally, the investigators collected samples of cancerous colon mucosa from 10 participants for the attempt to isolate F. nucleatum and P. gingivalis using the quantitative culture method.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 15 Jan 2025
- Start date
- 25 Oct 2023
- Primary completion date
- 30 Sept 2024
- Lead sponsor
- University Medical Centre Ljubljana
- Diseases
- Colorectal cancer
- NCT number
- NCT06799182
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 25 Oct 2023 to the primary completion date, 30 Sept 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- antibiotic therapy in the last 3 months
- chemotherapy or radiotherapy prior to surgical procedure
Other illness
- advanced stage cancer, scheduled for palliative care
Age
- under 18 years old
Other
- periodontal treatment in the past 12 months
- edentulism
Who the study is looking for
- colorectal cancer, scheduled for surgical treatment
- consent to participate
- Additional inclusion Criteria fot the control group:
- fiilled questionnaire
- Recorded CRP results at the first examination, after surgery, and at the first follow-up examination.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Medical Center Ljubljana, Division of stomatology, Center for oral disease and periodontology Coordinator of this site? Confirm its status | Ljubljana | Slovenia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.