NCT06799312Not yet recruiting
Comparative Effectiveness of Ipsilesional High-frequency rTMS, Contralesional Continuous Burst Theta rTMS, and Sham rTMS, Each Combined With Physiotherapy, in Subacute Ischemic Stroke Upper Limb Recovery : Clinical, Neurophysiological and Radiological
Comparative Effectiveness of Ipsilesional High-frequency rTMS, Contralesional Continuous Burst Theta rTMS, and Sham rTMS, Each Combined With Physiotherapy, in Subacute Ischemic Stroke Upper Limb Recovery : Clinical, Neurophysiological and Radiological: A Double-blinded Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 5 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
To compare the efficacy of lesional high-frequency rTMS, contralesional cTBS, and sham stimulation in improving motor and cognitive recovery in post-stroke patients undergoing physiotherapy.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 90 (estimated)
- First submitted
- 15 Jan 2025
- Start date
- 15 Mar 2025
- Primary completion date
- 30 Sept 2026
- Lead sponsor
- Assiut University
- Diseases
- Stroke
- NCT number
- NCT06799312
What you commit to
- Study type: Interventional
- Planned participants: 90
- From 15 Mar 2025 to the primary completion date, 30 Sept 2026
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe neglect or aphasia that would impede participation in therapy.
Other illness
- Hemorrhagic stroke or bilateral stroke.
- Severe cognitive impairment, defined as a Montreal Cognitive Assessment (MoCA) score \< 10.
- Contraindications to TMS, such as: History of epilepsy, Metallic implants in the head, Other contraindications based on TMS safety guidelines.
- Comorbid conditions that limit participation in rehabilitation.
Who the study is looking for
- First-ever ischemic stroke, confirmed by imaging.
- Stroke affecting the non-dominant hemisphere (cortical or subcortical) within the middle cerebral artery (MCA) territory.
- Acute to subacute stage of stroke (time since onset: 48 hours to 2 weeks).
- Ability to comply with the study protocol and interventions.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.