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NCT06804252Active, not recruiting

Incidence of Fragility Fractures and Osteoporosis Screening in Chronic Stroke Patients

Incidence of Fragility Fractures and Osteoporosis Screening in Chronic Stroke Patients: a Prospective Observational Study

Source: ClinicalTrials.gov · Last updated 5 Feb 2025

Brief summary (registry, in English)

Stroke is a known risk factor for the development of osteoporosis, leading to an increased risk of falls and fractures. Several international studies have associated stroke with hip fractures, showing an odds ratio ranging between 1.5 and 4. The literature frequently indicates a lack of management for bone metabolism in patients following cerebrovascular events. This study aims to evaluate the incidence of osteoporosis and fragility fractures in patients with chronic stroke. A secondary aim is to assess whether patients have been adequately screened for bone metabolism following a cerebrovascular event. This study is designed as a prospective observational study. Patients aged over 65 years with chronic stroke are assessed at the U.O.C. of "Functional Recovery and Rehabilitation" at A.O.U.P. "P. Giaccone," Palermo. During the assessment, clinical and demographic data are collected, including details of the cerebrovascular event (location, hemorrhagic/ischemic, date), pre-event and post-event disability/autonomy (Rankin scale), presence of fractures (location and date) in the patient's medical history (pre and post-event), femoral and lumbar DEXA for osteoporosis evaluation, and DeFRA for assessing the 10-year risk of fragility fractures.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
50 (estimated)
First submitted
18 Jan 2025
Start date
10 Dec 2024
Primary completion date
30 Jun 2025
Lead sponsor
University of Palermo
NCT number
NCT06804252

What you commit to

  • Study type: Observational
  • Planned participants: 50
  • From 10 Dec 2024 to the primary completion date, 30 Jun 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Patients with acute stroke
  • Severe cognitive impairment that prevents informed consent
  • Other major illnesses affecting bone metabolism (e.g., severe renal disease)
  • Patients with conditions that contraindicate DEXA scan

Other

  • Patients already undergoing treatment for osteoporosis

Who the study is looking for

  • Patients aged 65 years and older
  • Diagnosed with chronic stroke
  • Able to provide informed consent
  • Willing to participate in follow-up assessments
  • Stable medical condition that allows participation in the study

Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
A.O.U.P. P. Giaccone, Palermo, Italia 90127
Coordinator of this site? Confirm its status
PalermoItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.