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NCT06805877Active, not recruiting

Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing

Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing in Community Health Centers

Source: ClinicalTrials.gov · Last updated 25 Sept 2026

Brief summary (registry, in English)

Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the U.S. initiative to end the HIV epidemic, but healthcare providers lack tools to support PrEP discussions and prescribing for patients likely to benefit. This research will evaluate whether integrating automated tools into electronic health records to help providers efficiently and equitably identify potential candidates for PrEP, discuss PrEP, and prescribe PrEP can improve PrEP initiation and persistence in safety-net community health centers. It will achieve this by conducting a stepped-wedge trial of a decision support tool with an embedded HIV prediction model to identify patients likely to benefit from PrEP. The intervention will be delivered to healthcare providers in 16 community health centers within the national OCHIN network.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
16 (estimated)
First submitted
28 Jan 2025
Start date
21 Apr 2025
Primary completion date
31 Jul 2029
Lead sponsor
Harvard Pilgrim Health Care
Diseases
HIV
NCT number
NCT06805877

What you commit to

  • Study type: Interventional
  • Planned participants: 16
  • From 21 Apr 2025 to the primary completion date, 31 Jul 2029
  • 16 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Delivery site specializing in HIV or STI care

Other

  • Correctional facilities
  • Mobile sites
  • School-based health center sites

Who the study is looking for

  • Delivery site saw at least 500 distinct patients in 2024 during in-person or telehealth visits
  • Delivery site had at least 10 new HIV diagnoses or positive HIV screening tests in 2023
  • Delivery site provides primary care other than pediatrics, and the primary care department(s) were active on OCHIN Epic as of 1/1/2023

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (16)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Mercy Care Decatur Street
Coordinator of this site? Confirm its status
AtlantaUnited StatesUnknown status
Southwest Community Health Center 968 Fairfield Avenue
Coordinator of this site? Confirm its status
BridgeportUnited StatesUnknown status
Neighborhood Family Practice Ridge Community Health Center
Coordinator of this site? Confirm its status
ClevelandUnited StatesUnknown status
Bay Area Community Health Liberty Clinic
Coordinator of this site? Confirm its status
FremontUnited StatesUnknown status
Bee Busy Wellness Center Bray Oaks
Coordinator of this site? Confirm its status
HoustonUnited StatesUnknown status
Lynn Community Health Center 269 Union
Coordinator of this site? Confirm its status
LynnUnited StatesUnknown status
Mattapan Community Health Center Blue Hill
Coordinator of this site? Confirm its status
MattapanUnited StatesUnknown status
Lifelong East Oakland Health Center
Coordinator of this site? Confirm its status
OaklandUnited StatesUnknown status
TrueCare Oceanside Family Medicine
Coordinator of this site? Confirm its status
OceansideUnited StatesUnknown status
Variety Care Sequoyah
Coordinator of this site? Confirm its status
Oklahoma CityUnited StatesUnknown status
Signature Health Painesville
Coordinator of this site? Confirm its status
PainesvilleUnited StatesUnknown status
DAP Legacy
Coordinator of this site? Confirm its status
Palm SpringsUnited StatesUnknown status
Prism Belmont
Coordinator of this site? Confirm its status
PortlandUnited StatesUnknown status
One Community Health Midtown Campus
Coordinator of this site? Confirm its status
SacramentoUnited StatesUnknown status
Seattle Roots Community Health Carolyn Downs Community Clinic
Coordinator of this site? Confirm its status
SeattleUnited StatesUnknown status
Siouxland Community Health Center Sioux City
Coordinator of this site? Confirm its status
Sioux CityUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.