NCT06807112Not yet recruiting
The Influence of Secretin Stimulated Pancreatic Secretion on ctDNA Expression in Patients With Pancreatic Ductal Adenocarcinoma: The Role of Biomarkers in Determining the Prognosis of Pancreatic Ductal Adenocarcinoma
The Influence of Secretin Stimulated Pancreatic Secretion on Circulating Tumor DNA Expression in Patients With Pancreatic Ductal Adenocarcinoma: The Role of Biomarkers in Determining the Prognosis of Pancreatic Ductal Adenocarcinoma
Source: ClinicalTrials.gov · Last updated 4 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this study is to assess the influence of pancreatic secretion stimulation by intravenously administered secretin on circulating tumor DNA in patients with pancreatic ductal adenocarcinoma. Additional aim of the study is to analyse a role of specific biomarkers in determining the prognosis of this disease. The main question o answer is: Does intravenous secretin administration potentiate the release of circulating tumor DNA in patients with pancreatis ductal adenocarcinoma? Additional question is: Is there a biomarker specific and sensitive enough to help to predict the prognosis and the at the time status of the disease? Participants scheduled for surgical treament due to pancreatic ductal adenocarcinoma will be included and stimulated with intravenously administered secretin, their peripheral blood samples will then be analyzed for ctDNA levels.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 39 (estimated)
- First submitted
- 29 Jan 2025
- Start date
- Feb 2025
- Primary completion date
- Jun 2026
- Lead sponsor
- Charles University, Czech Republic
- Diseases
- Pancreatic cancer
- NCT number
- NCT06807112
What you commit to
- Study type: Observational
- Planned participants: 39
- From Feb 2025 to the primary completion date, Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- patients diagnosed with pancreatic ductal adenocarcinoma, at the time indicated for different than surgical therapy
Who the study is looking for
- patients diagnosed with pancreatic ductal adenocarcinoma
- patients indicated for surgery by multidisciplinary tumor board
- patients without previously administered chemotherapy
- patients with previously administered chemotherapy
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Surgery, Military University Hospital in Prague Coordinator of this site? Confirm its status | Prague | Czechia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.