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NCT06807684Recruiting

Abnormal Connectivity Involving the Social Reciprocity Network in Autism and the Impact of Neurostimulation in Mitigating the Abnormalities

Discerning the Abnormal Functional Connectivity Involving the Social Reciprocity Network in Autism Spectrum Disorder and the Impact of Transcranial Magnetic Stimulation in Mitigating the Abnormalities

Source: ClinicalTrials.gov · Last updated 21 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

There is no consensus regarding the neurological substrate underpinning ASD. The investigators describe the novel concept of "social reciprocity network" and hypothesize that aberrant connectivity/oscillatory patterns affecting this network contribute to the core deficits in ASD. The overarching goal of this trial is to explore abnormalities involving the neuronal connectivity and oscillatory patterns within the social reciprocity network and to elucidate the role of modulating this network via rTMS in improving the above measures and social cognition in ASD. Quantitative electroencephalography (QEEG) coherence and spectral power analysis are reliable measures of neuronal connectivity and dynamics. The investigators aim to study the QEEG coherence/spectral power analysis to explore the neuronal dynamics affecting the social reciprocity network in ASD.

Status (registry)
Recruiting
Study type
Interventional
Enrollment
12 (estimated)
First submitted
12 Aug 2024
Start date
Aug 2024
Primary completion date
Dec 2025
Lead sponsor
Christiana Care Health Services
Diseases
Autism
NCT number
NCT06807684

What you commit to

  • Study type: Interventional
  • Planned participants: 12
  • From Aug 2024 to the primary completion date, Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

  • 1\. Fulfilling the DSM-V criteria for ASD and confirmed by CARS2, HF Exclusion criteria
  • Patients with ASD exhibiting significant anxiety or contact avoidance, precluding them from cooperating with the procedure
  • Patients with a known diagnosis of seizures
  • Presence of any metallic implants or devices in the head or neck area
  • Pregnant women

Age in the registry: 13 years to 18 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Christiana Care
Coordinator of this site? Confirm its status
NewarkUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.