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NCT06809959Completed

Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients

Bifocal Transcranial Alternating Current Stimulation Targeting the Frontoparietal Network in Stroke Patients to Enhance Network Connectivity

Source: ClinicalTrials.gov · Last updated 15 May 2026

Brief summary (registry, in English)

Hand and arm function is often significantly impaired in stroke patients, making its recovery a primary goal in rehabilitative treatment. This study investigates the effects of bifocal transcranial alternating current stimulation (tACS) on the frontoparietal network in stroke patients during the subacute to chronic recovery phase. By using non-invasive brain stimulation, the study aims to modulate the neural network connectivity between the ipsilesional parietal and premotor cortices. Electroencephalography and kinematic data will be utilized to assess the impact of tACS on functional connectivity and its subsequent effect on motor function. The ultimate goal is to enhance functional coupling within these networks to promote motor function in stroke patients.

Status (registry)
Completed
Study type
Interventional
Enrollment
20 (actual)
First submitted
30 Jan 2025
Start date
3 Feb 2025
Primary completion date
11 Apr 2026
Lead sponsor
Universitätsklinikum Hamburg-Eppendorf
Diseases
Stroke
NCT number
NCT06809959

What you commit to

  • Study type: Interventional
  • Participants enrolled: 20
  • From 3 Feb 2025 to the primary completion date, 11 Apr 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Use of psychotropic medication
  • Pacemakers, other stimulators, or medication pumps
  • Non-MRI-compatible metallic implants or foreign objects in the body

Other illness

  • Presence of additional neurological or psychiatric disorders
  • Contraindications for transcranial alternating current stimulation (e.g., epilepsy, history of seizures, any type of pacemaker)

Other

  • Pregnancy or potential pregnancy in female participants
  • Claustrophobia

Who the study is looking for

  • First-ever clinical stroke
  • Signed informed consent
  • First-ever clinical ischemic stroke at least 3 months ago
  • Stimulation areas (PMv and IPS) are unaffected
  • Residual deficits in the upper limb

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Neurology, University Medical Center Hamburg-Eppendorf
Coordinator of this site? Confirm its status
HamburgGermanyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.