NCT06812780CompletedPhase 1
A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD2389
A Single Dose, Non-Randomised, Open-Label, Parallel Group Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD2389 (CAMPOLINA)
Source: ClinicalTrials.gov · Last updated 24 Sept 2025
Brief summary (registry, in English)
The purpose of this study is to examine the safety and tolerability of AZD2389 in participants with hepatic impairment and participants with normal hepatic function.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 35 (actual)
- First submitted
- 3 Feb 2025
- Start date
- 4 Feb 2025
- Primary completion date
- 4 Sept 2025
- Lead sponsor
- AstraZeneca
- NCT number
- NCT06812780
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 35
- From 4 Feb 2025 to the primary completion date, 4 Sept 2025
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Positive test for HIV at screening
- History of severe allergy/hypersensitivity or ongoing clinically important allergy/hypersensitivity
- History of severe dermatological disorders
Lab values
- Participant has eGFR \< 60 mL/minute/1.73 m2
Who the study is looking for
- For Hepatic:
- Participant with a diagnosis of stable hepatic impairment
- For Healthy:
- Participants who are overtly healthy as determined by medical evaluation including medical history, physical examination, and laboratory tests.
- All participants:
- \- Body weight ≥ 50 kg; BMI within the range of 18.0 to 42.0 kg/m2 (inclusive).
Age in the registry: 18 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| - Coordinator of this site? Confirm its status | Chandler | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Miami Lakes | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Orlando | United States | Unknown status |
| - Coordinator of this site? Confirm its status | Rialto | United States | Unknown status |
| - Coordinator of this site? Confirm its status | San Antonio | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.