NCT06812793Completed
Muscle Endurance in Children With Cystic Fibrosis
Do Children With Cystic Fibrosis Differ in Muscle Endurance? A Comparative Study
Source: ClinicalTrials.gov · Last updated 6 Jan 2026
Brief summary (registry, in English)
Cystic fibrosis (CF) is a genetic disorder affecting exocrine glands, leading to thick, viscous secretions that damage organs such as the lungs, pancreas, and reproductive system. Respiratory failure from CF lung disease is a major cause of morbidity and mortality, with chronic inflammation and infections disrupting mucociliary clearance. This results in declining respiratory functions, muscle strength, physical inactivity, and quality of life. While some studies compare respiratory and lower extremity muscle endurance in children with CF, none have evaluated core muscle endurance. This study aims to compare respiratory muscle strength, endurance, and muscle endurance in the core and lower extremities between children with CF and healthy peers.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 48 (actual)
- First submitted
- 3 Feb 2025
- Start date
- 5 Feb 2025
- Primary completion date
- 3 Nov 2025
- Lead sponsor
- Bezmialem Vakif University
- Diseases
- Cystic fibrosis
- NCT number
- NCT06812793
What you commit to
- Study type: Observational
- Participants enrolled: 48
- From 5 Feb 2025 to the primary completion date, 3 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Having an organ transplantation history
- Using systemic corticosteroids
Other illness
- Having a history of exacerbation in the last month
- Having had a respiratory tract infection in the last month
Other
- Not being able to cooperate with the assessment methods performed in the study
- Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study
- Not being able to cooperate with the assessment methods performed in the study
- Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study
Who the study is looking for
- Being between the ages of 6-18,
- Being diagnosed with Cystic Fibrosis according to the American Cystic Fibrosis Association consensus guideline,
- Having a forced expiratory volume in one second (FEV1) above 40% of the predicted value
- \- Being between the ages of 6-18
Age in the registry: 6 years to 18 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bezmialem Vakif University Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.