NCT06813417Active, not recruitingEarly phase 1
CAR T Therapy With GCAR1 for Relapsed Alveolar Soft Part Sarcoma
An Open Label Individual Patient Dose Escalation Study Investigating the Safety and Efficacy of Retreatment With GCAR1 in a Patient With Multiply Relapsed Alveolar Soft Part Sarcoma
Source: ClinicalTrials.gov · Last updated 10 Apr 2025
Brief summary (registry, in English)
A single patient study to determine whether GCAR1 is safe and effective for re-treatment of alveolar soft part sarcoma (ASPS) with GPNMB surface expression that has relapsed and is not responding to usual treatment.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Early phase 1
- Study type
- Interventional
- Enrollment
- 1 (actual)
- First submitted
- 28 Jan 2025
- Start date
- 30 Jan 2025
- Primary completion date
- 30 Jan 2030
- Lead sponsor
- University of Calgary
- Diseases
- Childhood cancers, Sarcoma
- NCT number
- NCT06813417
What you commit to
- Study type: Interventional · Early phase 1
- Participants enrolled: 1
- From 30 Jan 2025 to the primary completion date, 30 Jan 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Anti-cancer therapy within 21 calendar days prior to the first dose of lymphodepleting chemotherapy. If subject has received anti-cancer therapy, they must have recovered adequately from the toxicity and/or complications from the intervention prior to starting therapy as per the discretion of the Qualified Investigator/Co-Investigator
Other illness
- Any active uncontrolled infection
Other
- Pregnancy or nursing
Who the study is looking for
- The patient must provide informed consent
- Adequate organ function, defined as creatinine clearance \>30 ml/min and LVEF \>45%
Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Arthur J.E. Child Comprehensive Cancer Centre Coordinator of this site? Confirm its status | Calgary | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.