NCT06815302Recruiting
TURN-IT FOG: Improving Turning and Freezing of Gait in People With PD
TURN-IT FOG: A Novel Intervention to Improve Turning in People With PD and Freezing of Gait
Source: ClinicalTrials.gov · Last updated 28 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkinson's disease, as assessed by patients, clinicians, and wearable sensors, and 2) to explore whether two different rehabilitation intervention can reduce FOG and improve daily life mobility in people with FOG sufficiently to justify a clinical trial. Participants will: * Be randomly assigned to one of two intervention groups (turning-focused agility exercise or strength-based exercise) * Have one-on-one training sessions three times per week for 6 weeks * Perform in-lab assessments before beginning and after completing the study intervention * Use wearable mobility sensors during daily life to measure their walking and balance
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 3 Feb 2025
- Start date
- 2 Jun 2025
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- Oregon Health and Science University
- Diseases
- Parkinson disease
- NCT number
- NCT06815302
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 2 Jun 2025 to the primary completion date, 31 Dec 2026
- 3 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- excessive use of alcohol or recreational drugs
- recent change in medication
Other illness
- Major musculoskeletal or neurological disorders, structural brain disease, epilepsy, acute illness or health history, other than PD, significantly affecting gait and turning (i.e., musculoskeletal disorder, vestibular problem, head injury, stroke, cardiac disease)
- medical condition or medications that precludes moderate-intensity exercise
Other
- Montreal Cognitive Assessment (MoCA) ≤21 or inability to follow directions
- inability to stand and walk for 2 minutes without an assistive device
Who the study is looking for
- diagnosis of idiopathic PD from movement disorders neurologist with the United Kingdom Brain Bank criteria of bradykinesia with one or more of the following - rest tremor, rigidity, and balance problems not from visual, vestibular, cerebellar or proprioceptive conditions
- reporting FOG in the New Freezing of Gait questionnaire (N-FOGQ)
- Hoehn \& Yahr stages II-IV
- ages 50-80 years old
- cognitive ability sufficient to participate in testing procedures and exercise classes
- be willing and able to participate in exercise intervention 3x/week for 6 weeks
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of São Paulo, Bauru Campus Coordinator of this site? Confirm its status | Bauru | Brazil | Recruiting |
| Oregon Health and Science University Coordinator of this site? Confirm its status | Portland | United States | Recruiting |
| Arizona State University Coordinator of this site? Confirm its status | Tempe | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.