NCT06816056Recruiting
Manual Therapy in Hemophilic Arthropathy of the Ankle
Safety and Efficacy of Manual Therapy in the Treatment of Haemophilic Arthropathy of the Ankle. A Randomised Multicentre Clinical Trial
Source: ClinicalTrials.gov · Last updated 10 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Introduction: Haemophilic ankle arthropathy manifests as functional (deficit in muscle strength, mobility and proprioception), intra-articular degenerative alterations and chronic pain. Manual therapy techniques are characterised by treating the soft tissues with the aim of modifying their density, relieving pain, reducing tissue sensitivity and improving the ranges of mobility. The objective is to evaluate the safety and effectiveness of a manual therapy protocol in patients with haemophilic ankle arthropathy. Methods: Randomised crossover clinical trial. 13 patients with haemophilic ankle arthropathy from different regions of Spain will be recruited and randomised into two study groups (experimental and control). Each session of the experimental group will last 50 minutes, with 1 physiotherapy session per week for a period of 3 weeks. Patients will be evaluated at the beginning of the study, after the intervention and after a follow-up period of 4 weeks. The treatment programme includes 10 techniques that must be administered bilaterally. The study variables are the frequency of ankle haemarthrosis, range of movement, pressure pain threshold, pain intensity, joint status, biomechanical analysis of gait and balance, functionality and kinesiophobia. Expected results: To evaluate the safety of manual therapy in patients with haemophilia. To observe changes in pain, mobility, joint condition, stability and functionality of the ankle, and kinesiophobia.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 13 (estimated)
- First submitted
- 3 Feb 2025
- Start date
- 5 Feb 2025
- Primary completion date
- 21 Jul 2025
- Lead sponsor
- Investigación en Hemofilia y Fisioterapia
- Diseases
- Haemophilia
- NCT number
- NCT06816056
What you commit to
- Study type: Interventional
- Planned participants: 13
- From 5 Feb 2025 to the primary completion date, 21 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with neurological or cognitive disorders that prevent them from understanding the questionnaires and physical tests
- Failure to sign the informed consent document
Who the study is looking for
- Patients diagnosed with haemophilia A and B
- With severe haemophilia phenotype (<1% FVIII/FIX)
- Over 18 years of age
- With a medical diagnosis of ankle arthropathy and with clinical assessment using the Hemophilia Joint Health Score
- On prophylactic or on-demand treatment with coagulation factor VIII/FIX concentrates
Age in the registry: 18 years to 65 years · Sex: Male · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidad Católica San Antonio Coordinator of this site? Confirm its status | Murcia | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.