NCT06816953Enrolling by invitation
Cartilage Biomarkers and HEAD-US Score in Severe Hemophilia A Patients Receiving FVIII Prophylaxis
Cartilage Biomarkers and HEAD-US Score in Severe Hemophilia A Patients Receiving Low Dose FVIII Prophylaxis
Source: ClinicalTrials.gov · Last updated 10 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Patients with severe hemophilia A often develop joint complication requiring careful monitoring. This study aimed to compare the effectiveness of standard low dose weight-based FVIII concentrates (CFCs) prophylaxis with pharmacokinetic-guided extended half-life FVIII concentrates (eHLFVIII) using cartilage biomarkers and HEAD-US score.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 19 (estimated)
- First submitted
- 19 Jan 2025
- Start date
- 1 Apr 2024
- Primary completion date
- 30 Jan 2025
- Lead sponsor
- Chulalongkorn University
- Diseases
- Haemophilia
- NCT number
- NCT06816953
What you commit to
- Study type: Interventional
- Planned participants: 19
- From 1 Apr 2024 to the primary completion date, 30 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- patients with underlying condition affecting the joints such as osteoarthritis, metabolic bone disease, etc.
Who the study is looking for
- patients with severe hemophilia A
- previously receiving standard low dose FVIII prophylaxis 1-3 times per week for at least 6 months prior to enrollment in the project
- no history of FVIII inhibitor (\<0.6 Bethesda unit/ml)
- obtained consent from both patients and their parents
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pediatric Department, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital Coordinator of this site? Confirm its status | Bangkok | Thailand | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.