NCT06818240Recruiting
Transcranial Direct Current Stimulation Enhances Dual-task Performance in Stroke
Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex Enhances Dual-task Performance in People With Stroke
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
Stroke often impairs lower limb control, resulting in gait abnormalities and difficulties in dual-task performance, such as walking while engaging in cognitive activities. This study examines the effects of a single session of transcranial direct current stimulation (tDCS) targeting the left dorsolateral prefrontal cortex (DLPFC) on dual-task walking performance in individuals with chronic stroke. Using a cross-over design, participants will undergo two sessions (active or sham tDCS, 7 ± 2 days apart) of stimulation at 2 mA for 30 minutes. Walking performance will be measured using single and dual-task conditions combining motor (e.g., 20 m walk) and cognitive tasks (e.g., word association, random number recall). Primary outcomes include walking speed (m/s), stride length (m), and dual-task cost (DTC) for mobility and cognitive speed. The study aims to evaluate tDCS as a potential tool to reduce DTC, improve dual-task performance, and improve daily function and quality of life in stroke survivors. Results may guide the development of tailored dual-task interventions in stroke rehabilitation.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 23 Jan 2025
- Start date
- 1 Nov 2024
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- The Hong Kong Polytechnic University
- Diseases
- Stroke
- NCT number
- NCT06818240
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 1 Nov 2024 to the primary completion date, 28 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- unstable medical conditions, such as heart failure, uncontrolled hypertension, or cancer
- history of contraindications to tDCS, such as epilepsy or metal implants
- history of head injury, head surgery, or lower limb orthopedic issues
Other
- presence of other comorbidities that could interfere with gait
Who the study is looking for
- age between 50 and 80 years
- at least 6 months post-first-ever stroke with unilateral motor deficits
- ability to walk independently for at least 10 m without the use of walking aids
- a score of 24 or higher on the Mini-Mental State Examination (MMSE)
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hong Kong Polytechnic University Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Recruiting |
Related publications
- Transcranial direct current stimulation of the dorsolateral prefrontal cortex improves dual-task performance in people with stroke.J Neuroeng Rehabil · 2026 · PMID 41943073
This page is information, not medical advice. Discuss any trial with your doctor.