NCT06820450Recruiting
Pilot Study to Characterize the Endometriosis Steroidome and Its Link to Endocrine Disruptors and Vaginal Dysbiosis
STERONLINE: Steroidome and Exposome of Endometriosis Single-center Case-control Study
Source: ClinicalTrials.gov · Last updated 24 Jun 2026
Brief summary (registry, in English)
Endometriosis is a systemic, steroid-dependent, inflammatory disease characterized by the growth of endometrial-like tissue outside the uterus, affecting approximately 10 % of women of childbearing age. The etiology and pathophysiology of endometriosis is not completely understood to support effective treatment and prevention strategies. Despite the steroid dependency, little is known concerning the underlying metabolism of estrogen and other tightly related steroids. Moreover, shortening the long diagnostic delays is a major priority in endometriosis research.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 135 (estimated)
- First submitted
- 5 Feb 2025
- Start date
- 1 Jul 2025
- Primary completion date
- 1 Jul 2027
- Lead sponsor
- Nantes University Hospital
- Diseases
- Endometriosis
- NCT number
- NCT06820450
What you commit to
- Study type: Observational
- Planned participants: 135
- From 1 Jul 2025 to the primary completion date, 1 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Presence of other hormone-dependent pathologies (e.g. breast cancer, PCOS).
- Acute infection.
Other
- Intercurrent diagnosis of pregnancy.
Who the study is looking for
- Women aged 18 to 45
- Free, informed and written consent from the patient to participate in the study
- Good understanding of the French language
- Patient affiliated to or benefiting from a social security or similar scheme
- Specific inclusion criteria for each group:
- Group 1. Controls.
- Women with no laparoscopically confirmed signs suggestive of deep endometriosis.
- No clinico-biological criteria in favour of a diagnosis of endometriotic disease, nor any radiological signs (ultrasound or MRI) suggestive of endometriosis.
- Group 2. Cases of deep endometriosis.
- Newly diagnosed women (less than 12 months).
- Severe, deep endometriotic pathology with surgical indication (clinical examination, imaging tests, pre-operative findings).
Age in the registry: 18 years to 45 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Nantes Coordinator of this site? Confirm its status | Nantes | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.