NCT06824259Active, not recruiting
The Value of Dual-parametric Magnetic Resonance Combined With Regional Saturation Biopsy in Patients With Suspected Prostate Cancer
The Value of Dual-parametric Magnetic Resonance Combined With Regional Saturation Biopsy in Diagnostic Decision-making in Patients With Suspected Prostate cancer--a Single-center Prospective Randomized Controlled Study
Source: ClinicalTrials.gov · Last updated 21 Aug 2025
Brief summary (registry, in English)
The aim of this study was to investigate the value of dual-parameter magnetic resonance imaging(bpMRI) combined with regional saturation biopsy in the diagnosis of prostate cancer by means of a prospective randomized controlled study. The main questions it aims to answer are: Can bpMRI guide the timing of prostate puncture and avoid unnecessary prostate biopsy? Effectiveness of focal saturation biopsy versus systemic biopsy + targeted biopsy.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 5 Feb 2025
- Start date
- 14 May 2025
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Peking University First Hospital
- Diseases
- Prostate cancer
- NCT number
- NCT06824259
What you commit to
- Study type: Interventional
- Planned participants: 400
- From 14 May 2025 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- reatment with radiotherapy, chemotherapy and surgery before prostate puncture;
Other illness
- History of prostate cancer;
Other
- tPSA \>50ng/mL;
- Presence of contraindications to prostate puncture and inability to tolerate prostate puncture;
- Prostate multiparametric magnetic resonance images of poor quality or some sequences are missing.
Who the study is looking for
- Be 18 years of age or older.
- Compliance with clinical guidelines for indications for prostate puncture:
- suspicious prostate nodule detected on rectal palpation;
- suspicious lesion detected by transrectal ultrasound or magnetic resonance;
- tPSA \> 10 ng/mL;
- tPSA 4-10 ng/mL with f/t \< 0.16 or PSAD \> 0.15.
- Complete sequence of bpMRI of the prostate at our institution;
Age in the registry: 18 years to - · Sex: Male · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Peking University First Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.