NCT06827366Recruiting
Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)
Source: ClinicalTrials.gov · Last updated 5 May 2026
Brief summary (registry, in English)
The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may be at higher risk for colorectal cancer (CRC). The specific objectives of this study are to 1) develop a lifestyle intervention based on evidenced-based diet and lifestyle recommendations (i.e. those proposed by the World Cancer Research Fund (WCRF) and the French National Cancer Institute); 2) evaluate the effect of the intervention on the adherence to the target diet and lifestyle recommendations as well as other subjective health measures, including quality of life; 3) evaluate the effect of the intervention on anthropometrics.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 800 (estimated)
- First submitted
- 24 Oct 2024
- Start date
- 26 Jan 2026
- Primary completion date
- 15 Nov 2027
- Lead sponsor
- Centre Leon Berard
- Diseases
- Colorectal cancer
- NCT number
- NCT06827366
What you commit to
- Study type: Interventional
- Planned participants: 800
- From 26 Jan 2026 to the primary completion date, 15 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Extensive intestinal surgery such as colectomy or surgical resection of the colon
Other illness
- Under a strict diet such as meal replacements, diets for co-morbidities such as diabetes
- Chronic gastrointestinal illness (IBD, IBS, celiac disease)
- Colorectal cancer confirmed or history of a primary cancer
Other
- Immobile due to physical constraints (e.g. handicap that is not compatible with physical activities)
- Severe malnutrition
- Pregnant
- Participation in another lifestyle study
- NB : For this study, there is no exclusion period from other research, and participants can simultaneously take part in another study unless it concerns lifestyle.
Who the study is looking for
- Having read the information note and agreeing to participate
- Will and availability to be committed for a full year
- At high risk for CRC but CRC negative
- Affiliated to a health security system
- Having a score on the adherence to the recommendation lower than or equal to 7 out of 9 at baseline.
- Able to read, write and understand French
Age in the registry: 35 years to 74 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Leon Berard Coordinator of this site? Confirm its status | Lyon | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.