NCT06828354RecruitingPhase 3
A Study of SHR-A1811 in Subjects With Ovarian Cancer
An Open-label, Randomized, Multicenter Phase III Clinical Trial of SHR-A1811 Versus Investigator-selected Chemotherapy for Platinum-resistant Relapsed Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Source: ClinicalTrials.gov · Last updated 20 Apr 2026
Brief summary (registry, in English)
This is an open-label study to evaluate the safety and efficacy of SHR-A1811 for injection in subjects with ovarian cancer.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- First submitted
- 10 Feb 2025
- Start date
- 13 Mar 2025
- Primary completion date
- May 2027
- Lead sponsor
- Jiangsu HengRui Medicine Co., Ltd.
- Diseases
- Ovarian cancer
- NCT number
- NCT06828354
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 300
- From 13 Mar 2025 to the primary completion date, May 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe infections prior to initiation of study treatment.
Other illness
- Have uncontrolled or severe cardiovascular disease.
- With any active autoimmune disease or history of autoimmune disease.
- Patients with active hepatitis B or hepatitis C.
- Patients with active tuberculosis.
Other
- Symptomatic, untreated or active central nervous system metastases.
Who the study is looking for
- The subjects voluntarily joined the study and signed the Informed consent forms (ICF).
- Measurable disease, as defined by RECIST v1.1.
- The Eastern Cancer Cooperative Group (ECOG) performance status of 0 or 1.
- Life expectancy ≥ 12 weeks.
Age in the registry: 18 years to 75 years · Sex: Female · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Qilu Hospital of Shandong University Coordinator of this site? Confirm its status | Jinan | China | Recruiting |
| Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology Coordinator of this site? Confirm its status | Wuhan | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.