NCT06833164Completed
ERAP1,2 in Recalcitrant Warts
Serum ERAP1 and ERAP2 Levels in Patients With Recalcitrant Warts
Source: ClinicalTrials.gov · Last updated 18 Feb 2025
Brief summary (registry, in English)
The exact mechanisms underlying the contribution of cellular immunity in the eradication of human papillomavirus (HPV) infections remain obscure. Individuals who have treatment-resistant warts frequently have immune deficiencies. Amino-peptidases (ERAP1, ERAP2) of endoplasmic reticulum are essential for production of antigenic epitopes that attach to the Major Histocompatibility Complex (MHC) class I and activate T-lymphocytes or natural killer (NK) cells. Aim: To assess ERAP1 and ERAP2 serum concentrations in patients with resistant warts.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 200 (actual)
- First submitted
- 13 Feb 2025
- Start date
- 1 Oct 2022
- Primary completion date
- 20 Mar 2024
- Lead sponsor
- Benha University
- NCT number
- NCT06833164
What you commit to
- Study type: Observational
- Participants enrolled: 200
- From 1 Oct 2022 to the primary completion date, 20 Mar 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients on systemic steroids or other immunosuppressive treatments
Other illness
- Patients suffering from chronic systemic diseases
Other
- Patients with genital warts
- Immunocompromised individuals
- Pregnant women
Who the study is looking for
- Patients who had a history of incomplete clearance or recurrence following two or more electrocautery sessions and four or more cryocautery treatments and intralesional bleomycin.
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| faculty of medicine Benha University Coordinator of this site? Confirm its status | Banhā | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.