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NCT06834022Enrolling by invitation

Comparison of Neuromodulatory Treatment of Migraine Headache with Acupuncture and Transcranial Direct Current Stimulation

Source: ClinicalTrials.gov · Last updated 19 Feb 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

The goal of this clinical trial is to compare effects of the treatment with acupuncture and transcranial direct current stimulation (tDCS) in patients with migraine headache. The main questions it aims to answer are: * is tDCS more effective than acupuncture/placebo? * is there any difference in venous blood inflammatory parameters (CGRP (calcitonin gene related peptide), IL (interleukine) -6, IL-8. IL-10, SAA (serum amyloid A) and ESR (erythrocyte sedimentation rate) before/after treatment? * could these inflammatory parameters function as biomarkers of disease and/or indicators of treatment's efficacy? Participants will regularly fill out questionnaires (migraine diary) and their venous blood before/after treatment will be taken for analysis. Researchers will compare the effects of sham and verus treatment of both methods before and after treatment.

Status (registry)
Enrolling by invitation
Study type
Interventional
Enrollment
120 (estimated)
First submitted
11 May 2023
Start date
4 Apr 2023
Primary completion date
1 Dec 2025
Lead sponsor
University Medical Centre Ljubljana
Diseases
Migraine
NCT number
NCT06834022

What you commit to

  • Study type: Interventional
  • Planned participants: 120
  • From 4 Apr 2023 to the primary completion date, 1 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • status post brain surgery with open skull
  • metal implants
  • biologic drugs

Other illness

  • severe psychiatric disorders

Other

  • pacemaker
  • brain stimulators
  • pregnancy

Who the study is looking for

  • 4 migraine days per month
  • no acupuncture in the past
  • understanding of study design and ability to give informed consent

Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hospital dr. Petra Držaja
Coordinator of this site? Confirm its status
LjubljanaSloveniaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.