NCT06838013Recruiting
Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke
A Randomized Controlled Trial of Anodal Transcranial Direct Current Stimulation and Transcutaneous Electrical Nerve Stimulation for Improving Lower Limb Function in Stroke Patients
Source: ClinicalTrials.gov · Last updated 29 Sept 2026
Brief summary (registry, in English)
This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people with stroke. It is hypothesize that lower limb motor function can be best improved by combining anodal tDCS with TENS, when compared with sham-tDCS with TENS, anodal tDCS with placebo-TENS, or control training at improving ankle muscle strength, motor control of lower limbs, walking performance, functional mobility and community integration in people with stroke.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 92 (estimated)
- First submitted
- 16 Feb 2025
- Start date
- 1 Mar 2025
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- The Hong Kong Polytechnic University
- Diseases
- Stroke
- NCT number
- NCT06838013
What you commit to
- Study type: Interventional
- Planned participants: 92
- From 1 Mar 2025 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- have had one or more epileptic seizures within the year prior to the date of inclusion in the study;
- are currently involved in drug studies or other clinical trials.
Other illness
- have any additional medical, cardiovascular or orthopedic conditions that would hinder their treatment or assessment;
- have a cardiac pacemaker;
Other
- have aphasia or cognitive difficulties that may interfere with their comprehension of instructions;
- have an intracerebral metal clip;
- have a major somatosensory deficit
- have any contraindication to tDCS;
Who the study is looking for
- are between 50 and 85 years of age;
- have had a single stroke more than 6 months and less than 15 years;
- have at least 5 degrees of active ankle dorsiflexion in the antigravity position;
- are able to walk 10 m independently, with or without a walking aid;
- are able to score 6 or higher out of 10 on the abbreviated mental test;
- have no skin allergies (e.g. redness or itchiness after application of the electrical stimulation pads) to electrical stimulation or electrodes;
- are able to follow instructions and give informed consent.
Age in the registry: 50 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hong Kong Polytechnic University Coordinator of this site? Confirm its status | Hong Kong | Hong Kong SAR China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.