NCT06842095Recruiting
Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation
Investigating the Effects of Beta Transcranial Stimulation to Advance Stroke Rehabilitation
Source: ClinicalTrials.gov · Last updated 7 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training. However, responses to classical NIBS protocols are highly variable. Movement-related changes in specific brain rhythms have previously been shown to be related to recovery of hand/arm function after a stroke. The investigators propose to use NIBS to target movement-related activity in the beta band (13-30Hz) within the motor cortical regions of the brain. The investigators will use a type of NIBS called transcranial alternating current stimulation (tACS), which uses a sinusoidally-varying electrical current where the stimulation frequency is determined to be relevant to the underlying brain rhythms of interest, and the stimulation timed to coincide with specific phases of the hand/arm movement. The primary aim is to investigate whether beta-tACS improves upper limb movement in stroke survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 23 Oct 2024
- Start date
- 1 Feb 2025
- Primary completion date
- 28 Feb 2027
- Lead sponsor
- University of Oxford
- Diseases
- Stroke
- NCT number
- NCT06842095
What you commit to
- Study type: Interventional
- Planned participants: 60
- From 1 Feb 2025 to the primary completion date, 28 Feb 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Other neurological condition affecting movement (e.g. Parkinson's Disease, Multiple Sclerosis).
- Standard contraindications to non-invasive brain stimulation (TMS, tACS). including (but not limited to) the presence of intracranial metallic or magnetic hardware, seizures, pregnancy, and the presence of a pacemaker or other stimulators/implants.
Other
- Inability to follow task instructions.
- Insufficient verbal and written English to comprehend the study and provide informed consent.
Who the study is looking for
- Participant is willing and able to give informed consent for participation in the study.
- Aged 18 years or above.
- Clinical diagnosis of stroke affecting the upper limb, with sufficient ability to perform the upper limb reaching task.
- At least 3 months post-stroke and discharged from inpatient care.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Oxford Centre for Functional MRI of the Brain (FMRIB) Coordinator of this site? Confirm its status | Oxford | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.