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NCT06842758Active, not recruiting

Relationship Between Thoracic Hyperkyphosis and Fall Risk in Women with Fragility Vertebral Fractures

Source: ClinicalTrials.gov · Last updated 24 Feb 2025

Brief summary (registry, in English)

Multiple vertebral fragility fractures, one of the main complications of osteoporosis, are frequently associated with thoracic hyperkyphosis, which in turn leads to significant postural alterations. These biomechanical changes may increase fall risk, posing a critical clinical issue for elderly patients. However, the results of studies investigating the association between hyperkyphosis and fall risk are conflicting, highlighting the need for further research. This study aims to explore the correlation between the severity of thoracic kyphotic curvature and fall risk in patients with multiple fragility fractures undergoing osteoporosis treatment. Additionally, the study seeks to evaluate the role of physiotherapy in improving patients' functional and postural outcomes. A retrospective observational study was conducted, supplemented by a narrative literature review to contextualize the findings. Forty patients undergoing treatment at the Functional Recovery and Rehabilitation Unit (UOC) of P. Giaccone University Hospital in Palermo were enrolled and followed up via biannual phone interviews. Data were collected between May 2023 and May 2024, with a longitudinal assessment of outcomes from T0 (baseline) to T1 (12 months). The severity of the kyphotic curve was quantified using the Cobb method, while fall risk was assessed through the Berg Balance Scale. Participation in physiotherapy programs was analyzed to evaluate their impact on clinical and functional outcomes.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
40 (actual)
First submitted
18 Feb 2025
Start date
1 May 2023
Primary completion date
1 May 2024
Lead sponsor
University of Palermo
Diseases
Osteoporosis
NCT number
NCT06842758

What you commit to

  • Study type: Observational
  • Participants enrolled: 40
  • From 1 May 2023 to the primary completion date, 1 May 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • History of orthopedic surgeries involving the spine or lower limbs.
  • Treatments for cerebrovascular diseases.
  • Presence of balance disorders.
  • Active oncological diseases.

Other

  • Use of walking aids

Who the study is looking for

  • Women aged ≥65 years.
  • Presence of at least three documented vertebral fragility fractures.
  • Diagnosis of thoracic hyperkyphosis

Age in the registry: 65 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
A.O.U.P. P. Giaccone
Coordinator of this site? Confirm its status
PalermoItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.