NCT06842836Active, not recruiting
Evaluation of Alterations in the Gut Microbiota in Pediatric Bronchial Asthma
Evaluation of Alterations in the Gut Microbiota in Bronchial Asthma: a Feasibility Study in a Pediatric Population in the Alexandria Area.
Source: ClinicalTrials.gov · Last updated 15 Sept 2025
Brief summary (registry, in English)
Asthma constitutes a major chronic noncommunicable disease, globally it affects about 300 million people and the incidence has been steadily increasing in recent decades; it affects about 10% of children and is the leading chronic disease in childhood. The microbiota constitutes the collection of all microorganisms-bacteria, viruses, fungi, protozoa-that live in symbiosis with our bodies. Disruption of the microbiota during this critical period of development can cause asthma, allergies, and other immunological disorders. Therefore, it can be an important environmental factor that determines the transition of health to disease. The aim of the intended study is to evaluate and analyze the presence of possible alterations in the gut microbiota in a cohort of pediatric asthmatic subjects by collecting fecal samples.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 20 (actual)
- First submitted
- 19 Feb 2025
- Start date
- 6 May 2024
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
- Diseases
- Asthma
- NCT number
- NCT06842836
What you commit to
- Study type: Observational
- Participants enrolled: 20
- From 6 May 2024 to the primary completion date, 31 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking prolonged systemic therapy for the treatment of bronchial asthma;
Other
- Bronchial asthma classified as moderate persistent or severe persistent;
- Insurmountable language barrier.
- Ongoing antibiotic intake.
Who the study is looking for
- Signature of informed consent by Parents;
- Age between 6 and 9 years;
- Confirmed diagnosis of bronchial asthma at Alessandria Children's Hospital through spirometry investigation;
- Bronchial asthma classified as intermittent or mild persistent;
- Patients followed at the outpatient clinics of the SC Pediatrics of AOU SS Antonio e Biagio and C. Arrigo of Alessandria.
Age in the registry: 6 years to 9 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| SSD Laboratori di Ricerca (DAIRI) - AOU Alessandria Coordinator of this site? Confirm its status | Alessandria | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.