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NCT06843304Recruiting

The Intelligent Prevention And Control System And Strategy For The Whole Disease Cycle Of Diabetic Nephropathy

Source: ClinicalTrials.gov · Last updated 20 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open

Brief summary (registry, in English)

Diabetic nephropathy is one of the most severe microvascular complications of diabetes and a major cause of premature death and disability. It has become a leading cause of end-stage renal failure both in China and worldwide, consuming substantial medical resources. The establishment of a comprehensive regulatory system for the development and progression of diabetic nephropathy is a critical need for effective prevention and control. However, there is a lack of representative cohorts covering the entire disease cycle of diabetic nephropathy both domestically and internationally, creating technical bottlenecks in comprehensively describing its developmental patterns. This project aims to expand and integrate existing large-sample natural population cohorts and prospective follow-up cohorts covering the entire disease cycle of diabetes and diabetic nephropathy. It will construct a panoramic life database to identify risk factors, clinical phenotypes, and multimodal biomarkers at different disease stages. By integrating multi-organ interactions (e.g., kidney, eye), the project will establish novel imaging and functional assessment technologies for microvascular complications. Utilizing artificial intelligence to process multimodal medical data, it will build and validate risk prediction models and evaluation systems for the entire disease cycle of diabetic nephropathy. The project will develop effective intelligent prevention and treatment strategies for diabetic nephropathy, promote the adoption of new technologies, and establish a medical quality control system to provide services for medical institutions. Ultimately, it aims to improve and sustain medical quality, reducing the incidence of end-stage renal disease.

Status (registry)
Recruiting
Study type
Observational
Enrollment
2000 (estimated)
First submitted
20 Feb 2025
Start date
1 Jan 2024
Primary completion date
Dec 2026
Lead sponsor
Chinese PLA General Hospital
NCT number
NCT06843304

What you commit to

  • Study type: Observational
  • Planned participants: 2000
  • From 1 Jan 2024 to the primary completion date, Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Combined with autoimmune diseases and tumors
    • Type 2 diabetes patients undergoing renal biopsy
  • Gestational diabetes mellitus, special type diabetes mellitus
  • Patients with hereditary kidney disease
  • Combined with autoimmune diseases

Other

  • Incomplete medical records
  • Lack of fundus microvascular examination or new imaging technology examination results data
  • Diabetic nephropathy The indicators in the comprehensive assessment model of the risk of renal progression could not be obtained
  • There were pregnancy plans in the study period

Who the study is looking for

  • Age ≥18 years old, gender is not limited
  • Diagnosed with type 2 diabetes
  • A history of type 2 diabetes for more than 5 years
  • Negative proteinuria
  • Creatinine is normal
  • Good compliance, voluntarily sign informed consent
  • Age ≥18 years old, gender is not limited
  • Diagnosed with type 2 diabetes
  • Kidney damage (microalbuminuria or dominant albuminuria or renal insufficiency)
  • Have undergone renal puncture biopsy and have complete renal pathological diagnosis data
  • Sign informed consent voluntarily

Criteria the registry did not label

  • T2DM

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Chinese PLA General Hospital
Coordinator of this site? Confirm its status
BeijingChinaRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.