NCT06844006Active, not recruiting
Investigating the Impact of Nudging Cardiologists to Prescribe Class I Recommendations Foundational- and Additional Medical Therapy in Heart Failure Patients
Assessment of Digital Care on Clinical Impact and Efficiency Using a Stepped Wedge Cluster RCT in Heart Failure Patients: the ADMINISTER II Trial
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
This study investigates the impact of a nudge-based intervention on improving 2026 European Society of Cardiology guideline class I Foundational Medical Therapy (FMT) and Additional medical therapy (AMT) prescription among cardiologists. Using a stepped wedge randomized controlled trial design, we assess whether digital decision support-leveraging home monitoring and clinical data-enhances adherence to guideline-recommended medication titration. The primary outcomes include HF related hospitalization rates and all cause mortality.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 1320 (actual)
- First submitted
- 19 Feb 2025
- Start date
- 9 Oct 2026
- Primary completion date
- 9 Jan 2028
- Lead sponsor
- Medisch Spectrum Twente
- Diseases
- Heart failure
- NCT number
- NCT06844006
What you commit to
- Study type: Interventional
- Participants enrolled: 1320
- From 9 Oct 2026 to the primary completion date, 9 Jan 2028
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Allergies that make uptitration impossible.
- Severe psychological disorders.
Other
- Not understanding the Dutch Language.
- Admission to hospice or palliative care.
Who the study is looking for
- All heart failure diagnoses
- \>18 years
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| OLVG Oost Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Unknown status |
| Catharina Ziekenhuis Coordinator of this site? Confirm its status | Eindhoven | Netherlands | Unknown status |
| Medisch Spectrum Twente Coordinator of this site? Confirm its status | Enschede | Netherlands | Unknown status |
| St. Antonius Hospital Coordinator of this site? Confirm its status | Nieuwegein | Netherlands | Unknown status |
| Maasstad Hospital Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.