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NCT06847685Recruiting

Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

Mechanisms of Uterine Fluid Absorption During Early Pregnancy

Source: ClinicalTrials.gov · Last updated 9 Mar 2026

Brief summary (registry, in English)

The researchers are evaluating mechanisms of uterine fluid absorption during early pregnancy

Status (registry)
Recruiting
Study type
Observational
Enrollment
140 (estimated)
First submitted
21 Feb 2025
Start date
1 Feb 2025
Primary completion date
1 Feb 2029
Lead sponsor
Johns Hopkins University
NCT number
NCT06847685

What you commit to

  • Study type: Observational
  • Planned participants: 140
  • From 1 Feb 2025 to the primary completion date, 1 Feb 2029
  • 3 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Study subjects with endometrial cancer.
  • Study subjects with a history of endometrial ablation.
  • Study subjects with undiagnosed uterine bleeding.
  • Women with reproductive diseases that affect the endometrium (such as fibroids or uterine polyps that distort endometrial cavity).

Other

  • Pregnant women.
  • Study subjects with an intrauterine device (IUD).

Who the study is looking for

  • Subject must be a healthy woman between the ages of 18 and 45 years.
  • Women with diagnosed endometriosis or infertility (cases).
  • Women without a diagnosis of endometriosis or infertility (controls).
  • Subject must have regular menstrual cycles.
  • Subject must have a body mass index (BMI) between 18 and 40.
  • Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum.
  • Subject must be able to understand and provide consent to procedures and use/disclosure of protected health information.
  • No history of Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, hepatitis B, and HIV.
  • For IVF study subjects, a minimum endometrial thickness of 7mm at the time of sample collection.

Age in the registry: 18 years to 45 years · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (3)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Georgia
Coordinator of this site? Confirm its status
AthensUnited StatesNot yet recruiting
Johns Hopkins Hospital
Coordinator of this site? Confirm its status
BaltimoreUnited StatesRecruiting
Rutgers University
Coordinator of this site? Confirm its status
PiscatawayUnited StatesActive, not recruiting

This page is information, not medical advice. Discuss any trial with your doctor.