NCT06850623RecruitingPhase 2
Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
A Phase 2 Study to Investigate the Efficacy and Safety of Acoustic Cluster Therapy With Modified FOLFIRINOX in Patients With Locally Advanced Pancreatic Cancer
Source: ClinicalTrials.gov · Last updated 13 Oct 2026
Brief summary (registry, in English)
The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 15 Jan 2025
- Start date
- 19 Jun 2025
- Primary completion date
- 15 Dec 2026
- Lead sponsor
- EXACT Therapeutics AS
- Diseases
- Pancreatic cancer
- NCT number
- NCT06850623
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 25
- From 19 Jun 2025 to the primary completion date, 15 Dec 2026
- 10 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Any prior anti-cancer treatment for pancreatic cancer (e.g. chemotherapy, surgery, radiation). Palliative bypass procedure and bile duct stenting are allowed.
Who the study is looking for
- Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.
- Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CAMBRIDGE CANCER TRIALS CENTRE-Addenbrooke's Hospital Coordinator of this site? Confirm its status | Cambridge | United Kingdom | Recruiting |
| Gary Weston Centre- Imperial College Healthcare- Du Cane Road Coordinator of this site? Confirm its status | Hammersmith | United Kingdom | Recruiting |
| The Royal Marsden- Downs Road Coordinator of this site? Confirm its status | Sutton | United Kingdom | Recruiting |
| Beth Israel Deaconess Medical Center - Division of Hematology/Oncology Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
| Henry Ford Centre Coordinator of this site? Confirm its status | Detroit | United States | Recruiting |
| Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
| Allegheny General Hospital Coordinator of this site? Confirm its status | Pittsburgh | United States | Recruiting |
| Brown University Cancer Institute Coordinator of this site? Confirm its status | Providence | United States | Recruiting |
| HonorHealth Research Institute Coordinator of this site? Confirm its status | Scottsdale | United States | Recruiting |
| Stanford Cancer Center Palo Alto Coordinator of this site? Confirm its status | Stanford | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.