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NCT06851546Completed

Efficacy of Selective Laser Trabeculoplasty Targeting Nasal Versus Inferior 180-degree

Source: ClinicalTrials.gov · Last updated 7 Jan 2026

Brief summary (registry, in English)

The purpose of this study to optimize Selective Laser Trabeculoplasty (SLT) application when used in the management of open angle glaucoma (OAG)

Status (registry)
Completed
Study type
Interventional
Enrollment
13 (actual)
First submitted
24 Feb 2025
Start date
6 Jan 2025
Primary completion date
10 Nov 2025
Lead sponsor
Mayo Clinic
Diseases
Glaucoma
NCT number
NCT06851546

What you commit to

  • Study type: Interventional
  • Participants enrolled: 13
  • From 6 Jan 2025 to the primary completion date, 10 Nov 2025
  • 2 sites in 2 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous history of either laser treatment or intraocular surgery, except for non-complicated cataract surgery (performed \>6 months before SLT)
  • Current use of steroids (ocular, periocular, or systemic)

Other illness

  • History of ocular trauma

Other

  • Unwilling or unable to give consent
  • Unable to attend scheduled post-operative visits
  • Narrow angles
  • Retinal detachment
  • Active iris neovascularization or active proliferative retinopathy
  • Active uveitis
  • Monocular patients

Who the study is looking for

  • Age 18 years and older
  • Ability to comprehend the study procedures and agreement to proceed with primary SLT treatment
  • Diagnosis of primary or secondary open angle glaucoma or glaucoma suspects with ocular hypertension
  • Bilateral disease
  • Pre-SLT IOP \>21 mmHg measured at least twice during patient's lifetime with or without medication
  • Open angles with moderate to intense trabecular pigmentation
  • Mild to moderate visual field defects (24-2 standard mean deviations better than the Swedish interactive thresholding algorithm standard of 12 dB)
  • No adequate IOP control (low treatment compliance, substantial adverse effects with eyedrops, and at least 2 IOP measurements higher than the individualized target IOP)

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Eye Care Centre, Victoria General Hospital
Coordinator of this site? Confirm its status
HalifaxCanadaUnknown status
Mayo Clinic in Rochester
Coordinator of this site? Confirm its status
RochesterUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.