NCT06855355Enrolling by invitation
CBM588 Reduces Colorectal Polyp Recurrence
Clostridium Butyricum MIYAIRI 588 Reduces Colorectal Adenomatous Polyp Recurrence: A Randomized Crossover Trial
Source: ClinicalTrials.gov · Last updated 16 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this randomized crossover clinical trial is to evaluate the efficacy of Clostridium butyricum MIYAIRI 588 (CBM588) in reducing colorectal adenomatous polyp recurrence in adult patients with a history of colorectal polyps. The main questions it aims to answer are: * Does CBM588 reduce the recurrence of colorectal adenomatous polyps? * Does CBM588 lead to a sustained decrease in polyp burden over time? Researchers will compare a group receiving CBM588 in the first year to a group receiving CBM588 in the second year (after a washout period) to determine whether CBM588 effectively lowers polyp recurrence rates and adenoma prevalence.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 11 Feb 2025
- Start date
- 10 Mar 2017
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Kaohsiung Medical University
- NCT number
- NCT06855355
What you commit to
- Study type: Interventional
- Planned participants: 500
- From 10 Mar 2017 to the primary completion date, 31 Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of colorectal cancer or other gastrointestinal malignancies
- Diagnosis of inflammatory bowel disease or familial adenomatous polyposis
Other
- Use of antibiotics and other probiotics during the study period
Who the study is looking for
- Adults with a history of colorectal adenomas that had been completely removed by endoscopic resection within the past three years, and who presented with recurrent colorectal polyps detected during surveillance colonoscopy
- Willingness to undergo follow-up colonoscopies at study intervals
- No antibiotic or probiotic use for at least three months before study entry
- Written informed consent obtained
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kaohsiung Medical University Chung-Ho Memorial Hospital Coordinator of this site? Confirm its status | Kaohsiung City | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.