NCT06855953Not yet recruiting
Vitamin K and Cognition in Coronary Heart Disease (NutriCog)
Vitamin K Supplementation to Improve Cognition of Patients With Coronary Heart Disease: a Randomized Controlled Pilot Study
Source: ClinicalTrials.gov · Last updated 4 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The purpose of this pilot study is to obtain a preliminary assessment of the effect of VK supplementation on cognitive performance and vascular function in adults with stable Coronary Heart Disease (CHD)
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 20 Feb 2025
- Start date
- 17 Mar 2025
- Primary completion date
- Dec 2026
- Lead sponsor
- Montreal Heart Institute
- Diseases
- Coronary artery disease
- NCT number
- NCT06855953
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 17 Mar 2025 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent modification of medication (\<2 weeks)
Other illness
- Recent acute coronary syndrome (\<3 months) or recent coronary revascularization (bypass surgery or percutaneous coronary intervention, \<3 months)
- Cognitive impairment (based on telephone version of the Mini-Mental State Examination test, score \<19/23)
- Malabsorption disorder (advanced liver disease, Crohn's disease)
Lab values
- Known left ventricular dysfunction (LVEF \< 40%) or chronic heart failure
Other
- Warfarin (Coumadin) use
- Diagnosis of depression or uncontrolled anxiety
- Patient with auditory or vision impairments not properly corrected by glasses or hearing aids
- Unable to read the informed consent form or unable to understand the oral explanations provided by the assessor
Who the study is looking for
- Men and women
- Age 60 years and older
- Medically documented stable Coronary Heart Disease (CHD)
- Daily dietary intakes of phylloquinone \<150 mcg
- Non-consumption of vitamin K supplements (i.e. K1 or K2, singly or in combination with other nutrients), or other cognitive aids
- Good French or English understanding
- Physical exercise not exceeding 2.5 hours/week of moderate to vigorous aerobic activity
- Capacity and willingness to sign informed consent
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Montreal Heart Institute Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.