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NCT06856382Active, not recruiting

The Association Between Microplastics and Macrogenomics and Metabolomics in Gastric Cancer

Identification of Paraneoplastic and Intratumor Microplastics in Gastric Cancer and Their Association Analysis With Macrogenomics and Metabolomics

Source: ClinicalTrials.gov · Last updated 4 Mar 2025

Brief summary (registry, in English)

The aim of this study was to identify and quantify microplastics in blood, stool, and tumor surgical specimens from gastric cancer patients by analyzing the nature, type, and abundance of microplastics using laser direct infrared (LDIR) spectroscopy, scanning electron microscopy (SEM), and pyrolysis-gas chromatography-mass spectrometry (Py-GC/MS). Meanwhile, combining macro-genomic and metabolomic techniques to explore the association between microplastics and host microbiota and metabolic profiles, and to reveal the potential effects of microplastics on gastric cancer incidence and development will provide new insights into the relationship between microplastic contamination and gastric cancer, as well as an important scientific basis for future public health strategies and cancer prevention and control measures.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
20 (estimated)
First submitted
25 Feb 2025
Start date
1 Dec 2024
Primary completion date
31 Dec 2026
Lead sponsor
Dong Peng
NCT number
NCT06856382

What you commit to

  • Study type: Observational
  • Planned participants: 20
  • From 1 Dec 2024 to the primary completion date, 31 Dec 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients receiving neoadjuvant radiotherapy or chemotherapy;

Other illness

  • patients with other malignant tumors other than gastric cancer;

Other

  • patients with incomplete or unclear pathological data;
  • individuals who are not willing to participate in the study.

Who the study is looking for

  • age ≥18 years old;
  • diagnosed with gastric cancer by pathology before surgery and not receiving chemotherapy, radiotherapy or immunotherapy;
  • no history of other gastrointestinal diseases;
  • complete clinical data and basic information;
  • willing to participate in this study and sign an informed consent form.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
The First Affiliated Hospital of Chongqing Medical University
Coordinator of this site? Confirm its status
ChongqingChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.