NCT06856668Completed
A Megastudy of Single-Session Interventions for Depression
A Megastudy of Single-Session Interventions to Challenge Depression in American Adults
Source: ClinicalTrials.gov · Last updated 27 Jun 2025
Brief summary (registry, in English)
This project aims to learn if new kinds of digital single-session interventions (SSIs) for depression could be effective for American adults. Many existing SSIs are delivered in a simple text-based format. However, it might be that different kinds of SSIs (in terms of both content and style) also have potential for scalable impact. Specifically, this study will investigate the effectiveness of 11 innovative SSIs by comparing them to a passive control and to an existing SSI with established efficacy.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 7505 (actual)
- First submitted
- 27 Jan 2025
- Start date
- 11 Mar 2025
- Primary completion date
- 24 Jun 2025
- Lead sponsor
- Northwestern University
- Diseases
- Depression
- NCT number
- NCT06856668
What you commit to
- Study type: Interventional
- Participants enrolled: 7505
- From 11 Mar 2025 to the primary completion date, 24 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- At least 18 years old
- Able to read and write fluently in English
- Have enough access to the internet to complete two sessions over four weeks
- Score at least 10 on the PHQ-9 screen (suggesting moderate depression; Kroenke et al., 2001)
- Pass the bot check during the screening survey
- All participants who are randomized to an experimental condition (and therefore completed all baseline measures) will be included in analyses, except for participants who indicate at the end of either the baseline or week 4 session that they did not participate in the study seriously. Researchers will only keep data from the first survey session a participant begins.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwestern University Medical Social Sciences Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.