NCT06859918Recruiting
Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder
ASPE Subproject - Training to Understand and Navigate Emotions and Interactions (TUNE In)
Source: ClinicalTrials.gov · Last updated 13 Mar 2026
Brief summary (registry, in English)
The purpose of this study is to test a novel, cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder. The treatment, named TUNE In (Training to Understand and Navigate Emotions and Interactions), includes components to address the many behavioral domains involved in social functioning, including social motivation, social anxiety, social cognition, social skills, and generalization of the skills to community settings. The Investigators will test the efficacy of TUNE In to improve social functioning in adults with autism spectrum disorder (ASD), using a randomized controlled trial using the SRS-2 as the primary outcome measure.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 27 Feb 2025
- Start date
- 24 Mar 2025
- Primary completion date
- Dec 2027
- Lead sponsor
- University of Pennsylvania
- Diseases
- Autism
- NCT number
- NCT06859918
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 24 Mar 2025 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Major mood episode (major depressive episode, manic episode), psychotic symptoms, or a psychiatric hospitalization within the last 6 months
- A history of intellectual disability or low Shipley-2 score
Other
- Severe self-injurious or aggressive behaviors; or with suicidal or homicidal ideation or behaviors (e.g. suicide attempt) within the last 6 months
Who the study is looking for
- 18 years of age or older
- Meet ASD diagnostic criteria supported by an outside diagnostic evaluation and/or by the clinical and developmental information gathered from a phone screen
- Be willing to complete screening surveys (outcome measures)
- Social Responsiveness Score, Second Edition, self-report SRS survey score of greater than or equal to 60
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Brodkin Lab: Perelman School of Medicine, Department of Psychiatry, University of Pennsylvania Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.