NCT06861413CompletedPhase 1
A Phase 1 Study to Evaluate the Relative Bioavailability of a VX-828 Tablet Formulation
A Phase 1, Open-label, Randomized, Parallel Study to Evaluate the Relative Bioavailability of a Tablet Formulation of VX-828 in Healthy Adult Subjects
Source: ClinicalTrials.gov · Last updated 4 Jun 2025
Brief summary (registry, in English)
The purpose of this study is to evaluate the relative bioavailability of a VX-828 tablet formulation compared to a suspension and evaluate its safety and tolerability.
- Status (registry)
- Completed
- Phase (registry)
- Phase 1
- Study type
- Interventional
- Enrollment
- 68 (actual)
- First submitted
- 28 Feb 2025
- Start date
- 1 Apr 2025
- Primary completion date
- 5 May 2025
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Diseases
- Cystic fibrosis
- NCT number
- NCT06861413
What you commit to
- Study type: Interventional · Phase 1
- Participants enrolled: 68
- From 1 Apr 2025 to the primary completion date, 5 May 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of febrile illness or other acute illness that has not fully resolved within 14 days before the first dose of study drug
Other illness
- Any condition possibly affecting drug absorption
- Other protocol defined Inclusion/Exclusion criteria may apply.
Who the study is looking for
- Body mass index (BMI) of 18.0 to 32.0 kilogram per square meter (kg/m\^2)
- A total body weight of more than (\>) 50 Kg
- Nonsmoker or ex-smoker for at least 3 months before screening
- Participants of non-childbearing potential
Age in the registry: 18 years to 55 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Celerion - Tempe Coordinator of this site? Confirm its status | Tempe | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.