NCT06864715Recruiting
Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors
Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors (LIVE-WEL)
Source: ClinicalTrials.gov · Last updated 28 Apr 2026
Brief summary (registry, in English)
The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke survivors with subthreshold depression (SD).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 350 (estimated)
- First submitted
- 3 Mar 2025
- Start date
- 10 Apr 2026
- Primary completion date
- 1 Nov 2029
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Diseases
- Stroke
- NCT number
- NCT06864715
What you commit to
- Study type: Interventional
- Planned participants: 350
- From 10 Apr 2026 to the primary completion date, 1 Nov 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Diagnosed dementia and/or currently taking cognitive enhancers, amyloid-targeting medications, or orexin receptor antagonists
- high-risk alcohol or drug misuse
- receiving medications for mood disorders and a change in dose or type within the last 4 weeks
Other illness
- Stroke event unrelated to vascular risk factors (e.g., drug use) or transient ischemic attack
- high suicide risk or severe psychiatric illness (e.g., bipolar disorder and active psychosis) and/or actively taking antipsychotics
Other
- 24-item HDRS score \> or equal to 15 indicating moderate to severe depression
- Actively participating in psychotherapy
- Patient Health Questionnaire 9 score \> or equal to 10 and/or answers positive to Q9
- Diagnosed aphasia and/or severe cognitive impairments
Who the study is looking for
- Enrollment within 3-months +2 weeks of a first-time ischemic or hemorrhagic stroke
- 24-item HDRS score \< 15 indicating subthreshold depression defined as the absence of depressive symptoms or presence of mild symptoms of depression
- Single person income less than or equal to $45,000
- Residing in a community residence
- Ability to speak and read in English or Spanish
- Mini-MoCA score \> or equal to 11
Age in the registry: 55 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The University of Texas Health Science Center at Houston Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
Related publications
This page is information, not medical advice. Discuss any trial with your doctor.