NCT06866561Completed
The Effect of Aerobic Exercise on Bone Turnover Markers in Postmenopausal Patients
The Effect of Aerobic Exercise on Bone Formation and Resorption Markers And The Quality of Life Tests in Postmenopausal Osteopenic Patients
Source: ClinicalTrials.gov · Last updated 12 Mar 2025
Brief summary (registry, in English)
The aim of the study was to evaluate the effect of light-moderate aerobic exercise on BMD in postmenopausal osteopenic women using bone formation-resorption markers. Participants were randomized into two groups as aerobic exercise and control groups and followed for 12 weeks. At the beginning and at the 12th week, bone formation-resorption markers including procollagen type 1 N-terminal propeptide (P1NP), cross-linked C-telopeptide of type 1 collagen (CTX), osteocalcin, malondialdehyde, non-bone-specific total alkaline phosphatase, 25(OH)D3 and oxidative markers such as parathyroid hormone (PTH) were evaluated in serum and whether there was a difference between the 2 groups.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 45 (actual)
- First submitted
- 20 Feb 2025
- Start date
- 15 Nov 2022
- Primary completion date
- 15 Nov 2023
- Lead sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
- Diseases
- Osteoporosis
- NCT number
- NCT06866561
What you commit to
- Study type: Interventional
- Participants enrolled: 45
- From 15 Nov 2022 to the primary completion date, 15 Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Corticosteroid use,
- Immunosuppressive drug use,
- Hormone replacement therapy use
Other illness
- A history of traumatic or nontraumatic fractures in the past year,
- Thyroid hormone disorders,
- Parathyroid hormone disorders,
- Liver function disorders,
- Kidney function disorders,
- Chronic heart failure,
- A history of malignancy,
- A history of rheumatological diseases,
Other
- Vertebral compression fracture,
- Anticonvulsant and heparin use,
- Antiresorptive or anabolic agent treatments use
- Those who could not complete sessions due to mechanical pain exacerbated during aerobic exercise on a treadmill (such as knee and hip osteoarthritis, back pain, etc)
Who the study is looking for
- Postmenopausal women from Türkiye aged 45-65 years,
- Bone mineral density (BMD) T-scores between -1 and -2.5 ( measured by dual-energy X-ray absorptiometry)
Age in the registry: 45 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bursa Yüksek İhtisas Education and Research Hospital Coordinator of this site? Confirm its status | Bursa | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.