NCT06867926Recruiting
The Effect of Cardiac Rehabilitation on Oxidative DNA Damage and Inflammation in Patients With Coronary Artery Disease
Source: ClinicalTrials.gov · Last updated 2 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The objective of this study was to determine the levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG), an indicator of oxidative stress, and to demonstrate oxidative DNA damage in cardiac rehabilitation treatment in patients with coronary artery disease. Additionally, proinflammatory cytokines TNFα, IL-1β, and IL-6 levels were measured to evaluate the significance of cardiac rehabilitation treatment in patients with coronary artery disease and to assess the correlation between cytokine levels and 8-OHdG levels.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 16 Oct 2024
- Start date
- 15 May 2025
- Primary completion date
- 1 Jul 2025
- Lead sponsor
- TC Erciyes University
- Diseases
- Coronary artery disease
- NCT number
- NCT06867926
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 15 May 2025 to the primary completion date, 1 Jul 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Being on regular medication for the last 6 months
Other illness
- Having heart failure
- Unstable Angina Pectoris
- Complex ventricular arrhythmia
- Having orthopedic or neurological diseases that prevent exercise
- Having kidney-liver disease
- History of inflammatory diseases
- Having a history of cancer-immunologic disease
- Having a history of chronic diseases such as diabetes mellitus, hypertension, heart and kidney failure
Age
- being under 18 years of age
Other
- Having a pacemaker
- Exercise is contraindicated
Who the study is looking for
- Patients aged 18-65 years with a diagnosis of coronary artery disease and no contraindications to cardiac rehabilitation and exercise testing
- Patients who will undergo cardiopulmonary exercise testing before cardiac rehabilitation
- Patients whose cognitive status is sufficient to complete the study and who can cooperate
- 18 years of age or older
- Not having a chronic disease (such as uncontrolled diabetes mellitus, hypertension, heart and kidney failure)
- Not taking regular medication
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Erciyes University Faculty of Medicine Coordinator of this site? Confirm its status | Kayseri | Turkey (Türkiye) | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.