NCT06868888Recruiting
Rheological Functions of Erythrocyte in ESRD
The Effect of Osmotic Stress in Erythrocyte Rheology in ESRD Patients
Source: ClinicalTrials.gov · Last updated 11 Mar 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
End-stage renal disease (ESRD) disrupts erythrocyte deformability due to osmotic imbalances, oxidative stress, and uremic toxins, leading to impaired microcirculation and oxygen transport. Dysregulation of ion channels, particularly the Gardos channel, exacerbates dehydration and eryptosis, further compromising vascular integrity. Given the critical role of erythrocyte flexibility in oxygen delivery, this study investigates its relationship with aerobic capacity in ESRD patients, highlighting potential mechanisms of microvascular dysfunction
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 5 Mar 2025
- Start date
- 24 Aug 2022
- Primary completion date
- 20 Mar 2025
- Lead sponsor
- Chang Gung Memorial Hospital
- Diseases
- Chronic kidney disease
- NCT number
- NCT06868888
What you commit to
- Study type: Observational
- Planned participants: 40
- From 24 Aug 2022 to the primary completion date, 20 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Having orthopedic or muscular diseases
- Other concerned medical, psychological or physiological diseases
Other
- Under 20 years-old
- Hyperkalemia occurs within 3 month
- Pregnancy
- Other exercise contraindications
Who the study is looking for
- Receiving hemodialysis and medication at least for 6 weeks
- Kt/V score \> 1.2
Age in the registry: 20 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chang Gung University Coordinator of this site? Confirm its status | Taoyuan | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.