NCT06869447Recruiting
New York Better Breathing Study
Lung Cancer Better Breathing Study
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
This clinical trial evaluates the effects of whether breathing exercises at home can reduce symptoms and help stage I-III lung cancer survivors stay active. Over 70% of lung cancer survivors have trouble breathing, feel tired, and have lower levels of fitness. This is often because their breathing muscles are weaker after surgery. Many survivors find it hard to exercise, which affects their quality of life and overall survival. A training program to strengthen these muscles might reduce breathing problems, lower fatigue, and improve quality of life. Staying active could also help boost the immune system to fight cancer. Respiratory muscle training (RMT) involves a series of breathing and other exercises that are performed to improve the function of the respiratory muscles through resistance and endurance training. Participating in a home-based RMT intervention may reduce symptoms from cancer or treatment in lung cancer survivors.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 27 Feb 2025
- Start date
- 20 Apr 2026
- Primary completion date
- 15 Apr 2028
- Lead sponsor
- Roswell Park Cancer Institute
- Diseases
- Lung cancer
- NCT number
- NCT06869447
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 20 Apr 2026 to the primary completion date, 15 Apr 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Participant has in situ (stage 0) or metastatic (stage IV) disease at study entry.
- Any condition which in the investigator's opinion deems the participant an unsuitable candidate to participate in the study.
Other
- Has contraindications for respiratory muscle training (e.g., recent pulmonary embolism, aortic aneurysm, current pneumothorax).
- Unwilling or unable to follow protocol requirements.
Who the study is looking for
- Age ≥ 18 years of age.
- Able to speak, read and comprehend the English language
- Self-identify as non-Hispanic Black or White.
- Are \< 24 months of histologically confirmed invasive, non-metastatic, lung cancer diagnosis.
- Have received surgical treatment (primarily stage I, II and III) and have completed all cancer treatments (surgery, chemotherapy, radiation).
- Willing to provide biospecimen samples for the study (blood) which will be collected in the comfort of the patient's home by a mobile phlebotomy group.
- Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Roswell Park Cancer Institute Coordinator of this site? Confirm its status | Buffalo | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.