NCT06870799Recruiting
Comparing Closed Face Masks vs Surface Guided Radiation Therapy for Head and Neck Radiotherapy
Randomized Controlled Trial Comparing Closed Face Masks vs Surface Guided Radiation Therapy for Head and Neck Radiotherapy
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
At present, open-face masks are used only in patients with claustrophobic anxiety, while all other patients are still immobilized with closed masks, thereby overlooking the need for improvement in patient comfort. Closed face masks in patients undergoing head and neck irradiation have never been compared to no masks in the setting of a randomized clinical trial, but only in feasibility trials. A randomized clinical trial may establish the role of no masks in terms of patient comfort, preference and setup accuracy in all patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 24 Feb 2025
- Start date
- 12 May 2025
- Primary completion date
- May 2027
- Lead sponsor
- University of Zurich
- Diseases
- Head and neck cancer
- NCT number
- NCT06870799
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 12 May 2025 to the primary completion date, May 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior head and neck irradiation;
- Known or suspected non-compliance, drug or alcohol abuse;
Other
- Women who are pregnant or breast feeding;
- Intention to become pregnant during the course of the trial;
- Lack of safe contraception, defined as: Female participants of childbearing potential, not using and not willing to continue using a medically reliable method of contraception for the entire study duration, such as oral, injectable, or implantable contraceptives, or intrauterine contraceptive devices, or who are not using any other method considered sufficiently reliable by the investigator in individual cases;
- Inability to follow the procedures of the trial, e.g. due to language problems of the participant;
- Enrolment of the investigator, his/her family members, employees and other dependent persons.
- One of the following Tumor Types: Nasopharynx, Sinunasal, patients with CTV within 5 mm of eyes or spinal cord.
Who the study is looking for
- Written informed consent according to Swiss law and ICH/GCP regulations before any trial specific procedures;
- Indication for head and neck radiotherapy irrespective of tumor type;
- Age: ≥ 18 years old;
- Karnofsky performance status ≥70;
- Patients who are willing and able to comply with scheduled visits, treatment, and other trial procedures.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospital Zurich Coordinator of this site? Confirm its status | Zurich | Switzerland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.