NCT06872346Recruiting
Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice, RCT
Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice (PREDICT), Randomized Control Trial
Source: ClinicalTrials.gov · Last updated 7 Aug 2026
Brief summary (registry, in English)
The goal of this PREDICT is to assess a personalize approach to screening and management of cervical cancer testing. The investigators will evaluate patients who are due for a follow up cervical cancer screening in the primary care clinics in the Massachusetts General Brigham system. Patients will be randomized by clinic into three different arms (Arm 1: standard care, Arm 2: visit based reminders, Arm 3: visit based reminders and population health outreach)
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 7500 (estimated)
- First submitted
- 28 Feb 2025
- Start date
- 22 Jul 2026
- Primary completion date
- 22 Jul 2028
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Cervical cancer
- NCT number
- NCT06872346
What you commit to
- Study type: Interventional
- Planned participants: 7500
- From 22 Jul 2026 to the primary completion date, 22 Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- were diagnosed with cervical cancer/ CIN3+ prior to the most recent screening Pap or HPV test
Other
- have had their cervix removed
- are not English or Spanish-speaking.
Who the study is looking for
- have a cervix and are 21-70 years old
- receive care at a participating primary care practice (i.e. PCP team visit within past 3 years)
- have had a Pap and/ or HPV test within the past 3.5 years
- has a CCSM result that suggest a 5-year risk of developing CIN3+ that warrants surveillance at 1 or 3 years, diagnostic colposcopy, or treatment (i.e., above average risk).
- Inclusion of those up to age 70 is intended to identify individuals whose prior history does not meet screening exit criteria, and warrants surveillance or diagnostic care even though women with adequate prior screening can stop at age 65
Age in the registry: 21 years to 70 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Brigham Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.