NCT06872645Recruiting
Exploring Water-free Sodium Storage
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
The overarching goal of this proposal is to definitively establish if acute water free Na storage and release occurs, if the amount stored/released is of a quantity that is physiologically relevant, and if the location is intracellular vs. extracellular.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 10 (estimated)
- First submitted
- 6 Mar 2025
- Start date
- 3 Oct 2025
- Primary completion date
- 30 Jun 2028
- Lead sponsor
- Yale University
- Diseases
- Heart failure
- NCT number
- NCT06872645
What you commit to
- Study type: Interventional
- Planned participants: 10
- From 3 Oct 2025 to the primary completion date, 30 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- 1 or more episodes of peritonitis in the previous 6 months or active infection of the peritoneal dialysis catheter
Lab values
- Poorly controlled diabetes with hemoglobin A1C\>9%
- Anemia with hemoglobin \<8g/dL
- gastrointestinal disease that causes diarrhea or expectation of sodium losses in stool.
Other
- Inability to give written informed consent or follow study protocol.
- Urinary incontinence
- Body weight \< 60kg
- use of amiodarone in the last 6 months (which will interfere with tissue iodine ascertainment).
Who the study is looking for
- ESRD Patients actively undergoing PD with a reliably functioning PD catheter
- Systolic blood pressure \> 130 mmHg
- Serum sodium \>135 mmol/L
- daily urine output \< 400ml
- stable PD prescription for at least 2 months without requirement of 4.25% glucose PD solution
- PD vintage of at least 6 months
- Euvolemic as defined by the patient at their dry weight and free of any signs or symptoms of volume overload, per referring nephrologist
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Yale University Coordinator of this site? Confirm its status | New Haven | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.