NCT06874712Completed
Interest of LC-OCT for Diagnosing Inflammatory Dermatoses: ODIN (OCT Dermotoses INflammatoires)
Interest of LC-OCT for Diagnosing Inflammatory Dermatoses: Comparison of Images Obtained with LC-OCT and Those from Histological Sections "ODIN (OCT Dermatoses INflamaatoires)
Source: ClinicalTrials.gov · Last updated 13 Mar 2025
Brief summary (registry, in English)
Inflammatory dermatoses (eczematiform dermatoses, psoriasiform dermatoses, lichenoid dermatoses, toxic dermatoses, auto-immune and auto-inflammatory dermatoses, etc.) and their differential diagnoses (infectious or para-infectious dermatoses, deficiency dermatoses, etc.) are frequent reasons for dermatology consultations. These dermatoses are clinically heterogeneous eruptions for which a skin biopsy for histological examination may be routinely required to confirm the diagnosis. LC-OCT (DeepLive Damae Medical machine) is a new non-invasive skin imaging technique (using non-ionizing infrared light), enabling observation of skin tissue to a depth of 500 µm with a resolution of 1 µm (= "cellular" resolution, the keratinocyte, the main skin cell, measuring between 5 and 10 µm). This technique has already proved its worth in the diagnosis of skin cancers, and has the advantage of being non-invasive, painless and quicker than a biopsy. The investigators of the study want to study its value in the diagnosis of inflammatory dermatoses. During the consultation dedicated to skin biopsy, a cutaneous LC-OCT examination is routinely performed, but only for exploratory purposes, allowing better targeting of the most modified area. The aim of the study is to describe and analyze the characteristics of cutaneous imaging (LC-OCT) in inflammatory dermatoses, comparing them with the histological appearance of biopsy specimens. This is a preliminary study aimed at defining the value of LC-OCT in the diagnosis of inflammatory dermatoses, in the hope of replacing skin biopsy in the future.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 210 (actual)
- First submitted
- 7 Mar 2025
- Start date
- 1 Jul 2022
- Primary completion date
- 30 May 2024
- Lead sponsor
- Hospices Civils de Lyon
- Diseases
- Atopic dermatitis (eczema), Psoriasis
- NCT number
- NCT06874712
What you commit to
- Study type: Observational
- Participants enrolled: 210
- From 1 Jul 2022 to the primary completion date, 30 May 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- None
Who the study is looking for
- \- Age greater than or equal to 18 years.
- Definitive histopathological diagnosis of inflammatory dermatosis, including classification by type (eczematiform, psoriasiform or lichenoid) and subtype (e.g. atopic dermatitis for eczematiform dermatosis, lupus for lichenoid dermatosis, etc.).
- Availability of good-quality LC-OCT images/videos, with at least one interpretable 3D block, a video scanning lesional and healthy skin in a manner deemed "sufficient", as judged collegially by the authors.
Age in the registry: 18 years to - · Sex: All
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Service de Dermatologie, HEH, HCL Coordinator of this site? Confirm its status | France | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.