NCT06875206Not yet recruiting
Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke
Source: ClinicalTrials.gov · Last updated 24 Aug 2026
Brief summary (registry, in English)
This research will explore if brain stimulation combined with virtual reality therapy improves visual impairment. The stimulation technique is called low-intensity focused ultrasound stimulation (LIFUS). The treatment uses ultrasound to stimulate vision specific parts of the brain. Before this therapy, the participants will get structural brain imaging. Functional brain imaging will be performed before and after the study's completion to measure brain activity response to therapy. The purpose of this research study is to evaluate patients who have had a stroke between 6 and 24 months ago with a visual field impairment. The duration of active participation in the study is 1.5 months.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 28 (estimated)
- First submitted
- 11 Feb 2025
- Start date
- 1 Nov 2026
- Primary completion date
- 30 Jun 2028
- Lead sponsor
- Duke University
- Diseases
- Stroke
- NCT number
- NCT06875206
What you commit to
- Study type: Interventional
- Planned participants: 28
- From 1 Nov 2026 to the primary completion date, 30 Jun 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients will be excluded if they have a previous diagnosis of hemianopsia, a new diagnosis of central retinal ischemic injury, or visual blindness or a history of any other ocular disease.
Other illness
- Documented history of severe dementia with or without medication before stroke that affect subject's ability to participate in and be compliant to study protocol
- History of seizures
- Presence of any ultrasonic stimulation risk factors: an electrically, magnetically, or mechanically activated metal or nonmetal implant including cardiac pacemaker, intracerebral vascular clips, or any other electrically sensitive support system; non-fixed metal in any part of the body; pregnancy (the effect of ultrasonic stimulation on the fetus is unknown); preexisting scalp lesion or wound or bone defect or hemicraniectomy.
Other
- Significant upper motor deficits and the subject cannot do IVR sessions at the baseline
- Inability to get a new MRI
- Concerns about the inability to complete study visits/procedures by the PI.
Who the study is looking for
- ≥ 18 years old of any gender and race
- Clinical ischemic stroke or hemorrhagic (confirmed by CT or MRI) that occurred \>= 6-24 months ago
- Partial or complete homonymous hemianopsia on clinical exam
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Duke University Health System Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.