NCT06877312Recruiting
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
Longitudinal Study to Investigate Different Treatment Protocols of Transcranial Electrical Stimulation for Individuals With Dementia
Source: ClinicalTrials.gov · Last updated 4 Dec 2025
Brief summary (registry, in English)
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday). The study design is a longitudinal study design in which participants receive different tES randomly ordered. Treatments occur for 4 weeks, then 12 weeks of no treatment (wash-out period), repeated for each tES treatment type. Participants have the option of having their choice of music in the background while they perform cognitive exercises.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- First submitted
- 10 Mar 2025
- Start date
- 9 Oct 2024
- Primary completion date
- 31 Dec 2030
- Lead sponsor
- University of Manitoba
- Diseases
- Alzheimer disease
- NCT number
- NCT06877312
What you commit to
- Study type: Interventional
- Planned participants: 200
- From 9 Oct 2024 to the primary completion date, 31 Dec 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Plan to change the medication during any treatment period (5 weeks including the pre-post assessments)
Other illness
- Being diagnosed with Parkinson's disease, Parkinsonian dementia, Huntington disease, speech significant aphasia and intellectual disability, major depression/anxiety, bipolar disorder, schizophrenia or any other major mood disorder.
- Having a history of epileptic seizures or epilepsy
- Current substance abuse disorder
- Currently participating in another therapeutic study for dementia
Other
- Inability to adequately communicate in English
- Impaired vision or hearing severe enough to impair performance in cognitive tests
Who the study is looking for
- ability to read, write and speak English fluently
- MoCA score between 5 and 24
Age in the registry: 50 years to 95 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Riverview Health Centre Coordinator of this site? Confirm its status | Winnipeg | Canada | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.