NCT06877715Recruiting
Autistic Symptomatology and Sensory Profile in Children With Prader-Willi Syndrome
Source: ClinicalTrials.gov · Last updated 8 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Prader-Willi Syndrome (PWS) is a rare neurodevelopmental disorder stemming from genetic damage in the 15q11-q13 region, leading to hypothalamic dysfunction. Individuals with PWS often exhibit social interaction challenges, intellectual deficits, significant eating disorders, mood disturbances, and sensory-related autistic features. Although PWS is recognized by DSM-5 as a genetic cause of Autism Spectrum Disorder (ASD), ASD diagnosis in PWS remains rare in France. The CASSPER study aims to investigate the distinct autistic and sensory profiles in children with PWS, also analyzing the potential impact of early oxytocin treatment on these manifestations, in line with recommendations for early and tailored intervention.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 75 (estimated)
- First submitted
- 10 Mar 2025
- Start date
- 7 Apr 2025
- Primary completion date
- 30 Oct 2026
- Lead sponsor
- University Hospital, Toulouse
- Diseases
- Autism
- NCT number
- NCT06877715
What you commit to
- Study type: Observational
- Planned participants: 75
- From 7 Apr 2025 to the primary completion date, 30 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Change in psychotropic treatment (start, change in dose or discontinuation) in the past 3 months;
- Inability to provide clear information to parents/legal guardian;
- Not covered by social security.
Who the study is looking for
- Child with genetically confirmed PWS and identification of genetic subtype;
- Child aged between 3 and 16 years;
- Hospitalisation or multidisciplinary consultation planned for the child's routine follow-up at one of the investigating centres;
- No parental/legal guardian objection.
Age in the registry: 3 years to 16 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Children Hospital Coordinator of this site? Confirm its status | Toulouse | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.