NCT06877910Active, not recruiting
Deciphering the Molecular Traits of Non-canonical Responders to Advance Personalized Therapy in Gastric Cancer
Source: ClinicalTrials.gov · Last updated 14 Mar 2025
Brief summary (registry, in English)
Retrospective-prospective observational study in which a novel whole-exome sequencing (WES) approach will be used in association with whole-transcriptome sequencing (WTS) to analyze two independent and equally sized cohorts of patients with mGC.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 220 (estimated)
- First submitted
- 10 Mar 2025
- Start date
- 10 Jan 2021
- Primary completion date
- 20 Jun 2023
- Lead sponsor
- Regina Elena Cancer Institute
- Diseases
- Gastric and esophageal cancer
- NCT number
- NCT06877910
What you commit to
- Study type: Observational
- Planned participants: 220
- From 10 Jan 2021 to the primary completion date, 20 Jun 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous chemotherapy for metastatic disease;
- Comorbidities not controlled with adequate medical therapy;
Other
- Brain metastases;
- Patient unable to give adequate consent to the study.
Who the study is looking for
- Age \>18 years;
- Histological diagnosis of locally advanced or metastatic gastric cancer (GC) or gastroesophageal junction carcinoma (EJC);
- Adequate biological material for molecular analysis, collected (at surgery or by biopsy) before the administration of any anti-tumor treatment (chemotherapy and/or radiotherapy);
- ECOG PS 0-2;
- Adequate hematological, hepatic and renal function;
- Measurable disease according to RECIST criteria;
- Written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| IRCCS National Cancer institute Coordinator of this site? Confirm its status | Rome | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.