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NCT06878430Not yet recruiting

Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease

Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease: a Pilot and Development Study

Source: ClinicalTrials.gov · Last updated 9 Sept 2026

Brief summary (registry, in English)

The purpose of the DISCOVER study is to pilot acceptable approaches to people with covert cerebrovascular disease (CCD) and their follow-up. This is the first step in designing efficient randomised trials of treatments to reduce the risk of stroke or dementia in people with CCD.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
100 (estimated)
First submitted
6 Mar 2025
Start date
Oct 2026
Primary completion date
Dec 2026
Lead sponsor
University of Edinburgh
Diseases
Stroke
NCT number
NCT06878430

What you commit to

  • Study type: Observational
  • Planned participants: 100
  • From Oct 2026 to the primary completion date, Dec 2026
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Text of brain scan report unreadable
  • Do not consent to take part in study procedures
  • Unable to consent
  • Unable to communicate by email, letter or telephone through language, speech disability or lack of address
  • Unlikely to survive one year past enrolment in judgement of the study investigator

Who the study is looking for

  • People who, at the time the letter is prepared or are identified by a clinician
    • Age ≥ 65 years
    • Have no known history of:
    • Stroke or TIA
    • Dementia
    • Parkinson's disease
    • Multiple sclerosis
    • Metastatic cancer (or non-meningioma brain tumour).
    • A CT or MRI scan report ≤5 years before study start date with of one or more of:
    • Cerebral small vessel disease
    • Deep old ischaemic stroke
    • Cortical old ischaemic stroke

Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.